Progetti di ricerca

DIPARTIMENTO DI FARMACIA DELL’UNIVERSITA’ DI PISA

UNITA’ RICERCA:

responsabile Patrizia Davini

📞Tel 050 2219501

email: patrizia.davini@unipi.it, ricerca@farm.unipi.it

orario ricevimento: Lun-Ven dalle 11:00 alle 13:00

 

PROGETTI DI RICERCA ISTITUZIONALE 


PROGETTI DI RICERCA ATTIVI:

responsabile scientifico Titolo
DA POZZO Eleonora
(ex Martini)
PRIN2022 “Exploiting miCrogliAl exosome biogenesis and release: roles of cholesterol and oRGanelle cOntact sites”, acronimo “CARGO”,
LA MOTTA Concettina RE-Berry per la Bellezza da Riciclo Creativo: Valorizzazione dello Scarto di Trasformazione del Mirtillo Nero Pistoiese per lo Sviluppo di Crema Gambe per la Riattivazione del Microcircolo
LA MOTTA Concettina “Ruolo delle analisi computazionali nello sviluppo di nuovi biomarcatori e farmaci innovativi nei pazienti con glioblastoma”  (prog. n.309/22)
Capofila AOUP
GRANCHI Carlotta GR-2021-12374267 – The theranostic value of STARD3 in colorectal cancer
capofila CRO Aviano
MARCHETTI Laura “Precision neurotrophin intranasal delivery: BDNF meets extracellular vesicles for Prader-Willi Syndrome treatment”
DA POZZO Eleonora “Hub multidisciplinare e interregionale di ricerca e sperimentazione clinica per il contrasto alle pandemie e all’antibioticoresistenza (PAN-HUB)” (codice locale progetto T4-AN-07),  Traiettoria 4 del Piano Sviluppo e Coesione Salute – FSC 2014-2020 capofila UNIPI Informatica
TRINCAVELLI Maria Letizia “Sviluppo di radiotraccianti PET mirati al GPR17 per indagare la fisiopatologia della sclerosi multipla e migliorare le strategie diagnostiche”
capofila UNIMI
PICCARDUCCI Rebecca “Targeting PKCε activation in ApoE4 neurons as a synapse-restoring and neuroprotective approach for precision therapy in AD (PKC4AD)”
LA MOTTA Concettina “Targeting ALDH1A3 and investigating mechanisms of ALDH1A3-mediated breast cancer progression “,
TESTAI Lara Convenzione operativa “Valorizzazione di estratti a base di funghi come donatori di solfuro di idrogeno”
TESTAI Lara Convenzione operativa “Estratto innovativo ottenuto dalle mele e analisi  degli effetti benefici sull’omeostasi metabolica”
TESTAI Lara Convenzione Operativa “Valutazione dell’attivitĂ  antiossidante di n. 1 estratto  di Conifere e n. 1 estratto di Castagno”
TESTAI Lara Convenzione Operativa “Valorizzazione nutraceutica di estratti vegetali derivanti da parti di scarto e ottenuti con metodiche sostenibili
TUCCINARDI Tiziano  Precision Oncology for Ovarian Cancer: AI-Enhanced Analysis of Immunocompetent Organoids in Microfluidic Systems – RF-2024-12377253 Acronimo: AI-PROMISE    –   capofila CRO Aviano
MARCHETTI Laura Precision targeting of BDNF/TrkB-FL Pathway with Synapse Rewiring Quanta for Alzheimer’s Therapy (Acronym: SynReQuanta)
capofila Univ.Barcellona
TALIANI Sabrina Bando Proof-of Concept (PoC) Spark Pisa 2026 – progetto RECAST
MARCHETTI Laura Bando Proof-of Concept (PoC) Spark Pisa 2024 – progetto TARGET
MARZO Tiziano Bando Proof-of Concept (PoC) Spark Pisa 2025 – progetto TRIUMPH

 

PROGETTI DI RICERCA CONCLUSI:

responsabile scientifico titolo
Chiara Giacomelli (Claudia Martini) PNRR-CN3 “Sviluppo di Terapia Genica e farmaci con tecnologia a RNA”
Vincenzo Calderone PNRR-THE “Nanotechnologies for diagnosis and therapy”
Eleonora Da Pozzo PNRR-THE “Precision Medicine & Personalized Healthcare”
Marco Macchia PNRR-THE “Precision Medicine & Personalized Healthcare”
Filippo Minutolo PNRR-PE06 HEAL Italy
Simone Brogi PNRR-PE-BAC “One Health Basic and Translational Research Actions”
Marinella De Leo PNRR-CN-BAC “B4Web Una tassonomia biomolecolare…..sul web”
ASCRIZZI Roberta PRIN2022PNRR “CANTINA 5.0”
BARRESI Elisabetta PRIN2022PNRR “MILESTONE: Mitochondrial delIvery of goLd-bearing complExeS with Tspo ligands for Ovarian caNcEr treatment”
GIACOMELLI Chiara PRIN2022PNRR  “New insights into endometriosis pathogenesis: role of sphingosine 1-phosphate in neutrophil activation PROSPECT”
LAMOTTA Concettina PRIN2022PNRR  “Environment bioremediation from toxic aldehydes using a versatile Aldehyde Dehydrogenase endowed with broad substrate specificity”
MARTELLI Alma PRIN2022PNRR “Health promotion and neuropathic pain prevention through glymphatic system modulation: a sex/gender perspective”
RAPPOSELLI Simona PRIN2022PNRR “Glucose-6-phosphate dehydrogenase (G6PD) inhibitors for treatment of NAFLD-related hepatocellular carcinoma: synthesis and bio-pharmacological characterization”
CALDERONE Vincenzo PRIN2022 “SULFUR COMPOUNDS AND TRANSSULFURATION PATHWAY IN DIABETIC VASCULAR INJURY: ROLE, PLAYERS AND PHARMACOLOGICAL MODULATION (STraDiVaRy)”
DEMONTIS Giancarlo PRIN2022 “Astrocytes gain molecular control over visual cortex plasticity and function”
CITI Valentina PRIN2022 “Hydrogen sulfide releasing isothiocyanates as ferroptosis inhibitors for prevention of cardiovascular diseases”
DA SETTIMO PASSETTI Federico PRIN2022 “MitoMedChem for neurodegeneration”
DANIELE Simona PRIN2022 “Development of nano/micro-engineered devices for applications in peripheral nervous system pathological models (ENGInerve)”
GARGINI Maria Claudia PRIN2022 “Novel epigenetic modifiers for a mutation-independent pharmacological approach to extend photoreceptor survival in Retinitis Pigmentosa – RePiSTOP”
GUAZZELLI Lorenzo PRIN2022 “A seed for the green transition. Tailoring Deep Eutectic Solvents for 5-Hydroxymethylfurfural (HMF) transformation. (Acronym: SEED4GREEN)”
LA MOTTA Concettina PRIN2022 “Fluorescent and Gadolinium-based Probes for the Targeted Surgery and Neutron Capture Therapy of Glioblastoma”
MARZO Tiziano PRIN2022 “Biocompatible nanostructures for the chemotherapy treatment of prostate cancer”
MINUTOLO Filippo PRIN2022 “Development of innovative preclinical ready pan-coronavirus antivirals: prepare to look forward (Acronym: DIRECT)”
NENCETTI Susanna PRIN2022 “A comprehensive understanding of the molecular mechanisms involved in Cardiomyocyte dysfunction Induced by transthyretin Amyloid aggregates: evaluation Of NEw stabilizers of transthyretin misfolding (CIAONE)”
NIERI Paola PRIN2022 “Mediterranean marine organisms as sources of new anti-inflammatory and pro-resolving compounds”
PINESCHI Mauro PRIN2022 “ACHIEVING MOLECULAR DIVERSITY BY METAL-CATALYZED TANDEM REACTIONS”
TESTAI Lara PRIN2022 “Role of the hydroxyl carboxylic acid receptor type 2 in the social isolation-induced neurometabolic changes: possible intervention through dietary conditioned regimen and their pharmacological modulation”
TRINCAVELLI Maria Letizia PRIN2022 “Insight into the molecular mechanisms of pulmonary fibrosis: new targets to control the switch from fibrotic to regenerative fibroblast phenotype – SMILE”
PIRAS Anna Maria (ex ZAMBITO Ylenia) PRIN2022 “Immunological TArgeting of CAncer cells through Mvs-mediated tagging”
Zambito Ylenia PRIN2020 “SVILUPPO DI INIBITORI VEGFR/TUBULINA E POMPA DI EFFLUSSO CARICATI SU NANOCARRIER RIVESTITI CON MEMBRANA CELLULARE REATTIVA AGLI STIMOLI PER IL TRATTAMENTO DEI TUMORI METASTATICI” – D.D. MUR 80 25/01/2022
Nieri Paola BIORAS-SHRIMP ERA-NET Cofund on Blue economy – BlueBio H2020
Trincavelli Maria Letizia bando Ricerca salute 2018 “TRITONE” “Smart Bioactive personalised and implantable 3D printed scaffold for tendon regeneration”
Piras Anna Maria  “AEROPLAS 19” ex bando Ricerca COVID-19 Toscana
Rapposelli Simona bando Ricerca salute 2018 “DEM-AGING” “Neurodegenerative disorders throughout the lifespan. […]
Tuccinardi Tiziano Programma di rete NET-2016-02363765 “Patient phenotyping and genotyping and innovative treatment for retinitis pigmentosa”
Christian Pomeli (ex Chiappe)  “Innovative (pre)POmace Valorization procEsses” –  acronimo ImPrOVE – Call SUSFOOD2
Martini Claudia “OPTIMISED” ex bando Ricerca COVID-19 Toscana
Braca Alessandra TUSCAVIA POR FESR 2014-2020 R&s 2020 – Regione Toscana
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