Francesca Corsi


Francesca Corsi


Phone: 0502229537



Prof.ssa Maria Claudia Gargini

PhD project Title:

Saffron treatment as nutraceutical strategies for a mutation-independent approaches to slow down Retinitis Pigmentosa (RP)

Research summary:

Retinitis Pigmentosa (RP) is a hereditary retinal dystrophy characterized by the progressive degeneration of photoreceptors and abnormalities in retinal pigment epithelium. The purpose of my PhD project is to fill a gap in current knowledge of RP by devising a still missing pharmacological treatment which exploits the ability of new molecules to target oxidative stress and delay the disease progression. In particular, I will study the efficacy of a treatment based on saffron and its natural and synthetic derivatives, in slowing down the progression of retinal degeneration in animal models of RP.


Orcid id:



Poster communications at congress:

Corsi F., Piano I., Cerri C., Di Paolo M., Bisti S and Gargini C. “Electrophysiological analysis of retinal function in a neurodegenerating animal model treated with nutraceutical molecules”. Innovative Researches in Pharmaceutical and Environmental Sciences (IRPES) – Pisa 4 Dicembre 2020

Corsi F., Piano I., Polini B. and Gargini C. “Genetic modulation of anti-oxidant nutraceutical molecules slows down retinal degeneration in a mouse model of Retinitis Pigmentosa”.  3rd Brainstorming Research Assembly for Young Neuroscientists (BRAYN) – Pisa 25-26 Novembre 2020


Corsi F., Piano I., Guazzelli L., D’Andrea F., Sartini S., Giorgelli F., Confini G., Quattrini L., Nencetti S., Orlandini E., La Motta C. and Gargini C. “Diabetic retinopathy: evaluation of the efficacy of new synthetic molecules in an in-vitro model of hyperglycemia” Innovative Researches in Pharmaceutical and Environmental Sciences (IRPES) – Pisa 27 Novembre 2019

Piano I., Corsi F., Biagioni M., Novelli E., Ghidoni R., Gargini C. and Strettoi E. “Pharmacological strategies to slow down cone death and vision loss in animal models of Retinitis Pigmentosa” Institute of Neuroscience CNR (IN_CNR) Annual Retrat 2019 – Pisa 2-4 Ottobre 2019

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